Not all settings are required for your initial setup and first moves (or even a test cut). Some such as VFD and Ethernet setup may make things slightly more complicated while you're getting up and running, so will be covered in their own separate wiki sections.
The following settings are suggested as the first things to do while testing your new PrintNC grblHAL setup.
General ioSender setup - Settings: App
Initial grblHAL settings - Settings: Grbl
Once you have all of the axes and limit sensors tested and working correctly, you should move on to Homing and Gantry Squaring to get your machine to a safe and repeatable state from which you can start